India’s active COVID cases breach 11 lakh-mark; Govt prohibits export of Remdesivir vaccine



NEW DELHI: In view of increased demand for Remdesivir due to a surge in COVID-19 cases, the Centre on Sunday said the export of the antiviral injection and its Active Pharmaceutical Ingredients (API) has been banned till the situation improves.
In addition, to ensure easy access of the drug, which is used in treatment of coronavirus, to hospitals and patients, all domestic manufacturers of Remdesivir have been advised to display on their website details of their stockists and distributors, the Union Health Ministry said.
Drugs inspectors and other officers have been directed to verify stocks, check malpractices and also take other effective actions to curb hoarding and black marketing. State health secretaries will review this along with drug inspectors of the respective states and UTs, it said.
“India is witnessing a recent surge in COVID cases. As on April 11, there are 11.08 lakh active cases and they are steadily increasing. This has led to a sudden spike in demand for Remdesivir injection used in treatment of COVID patients,” the ministry said.
There is a potential for further increase in this demand in the coming days, it stated.
Seven Indian companies are producing the injection under voluntary licensing agreement with M/s. Gilead Sciences, USA. They have an installed capacity of about 38.80 lakh units per month, the ministry said.
“In light of the above, Government of India has prohibited the exports of Remdesivir injection and Remdesivir Active Pharmaceutical Ingredients (API) till the situation improves,” it said.
The Department of Pharmaceuticals has been in contact with the domestic manufacturers to ramp up the drug’s production, it added.
Government of India has also advised states that the extant ”National Clinical Management Protocol for COVID-19”, which is based on evidence, has been developed after many interactions by committee of experts and it is the guiding document for treatment of COVID-19 patients.
In the protocol, Remdesivir is listed as an investigational therapy, i.e. where informed and shared decision making is essential, besides taking note of contra indications mentioned in the detailed guidelines, the ministry said.
States and UTs have been advised that these steps should again be communicated to all hospitals, both in public and private sector, and compliance monitored, it added.
The active COVID-19 cases in India have breached the 11 lakh-mark for the first time after a record high of 1.52 lakh new infections while a massive vaccination push, dubbed by Prime Minister Narendra Modi as the beginning of another major war against coronavirus, was launched on this morning in a bid to abate the surge.
The active caseload till now was at its lowest at 1,35,926 on February 12 and at its highest at 10,17,754 on September 18, 2020.
Amid an unprecedented burden on health infrastructure in 15 states and Delhi, which are witnessing an upward trajectory, authorities have started reserving more COVID hospitals and taking steps to address any shortage of medical supplies, besides enhancing curbs on the movement of people.
The Centre announced a ban on export of Remdesivir, used in coronavirus treatment and its Active Pharmaceutical Ingredients, and asked all domestic manufacturers to display on their website details of their stockists and distributors.
There were some reports of shortage of drugs from a few states.

India’s COVID-19 tally of cases climbed to 1,33,58,805, and the death toll increased to 1,69,275 with 839 daily new fatalities, the highest since October 18, 2020, the data updated by Health Ministry on Sunday morning showed.
While the cumulative number of COVID-19 vaccine doses administered in the country has crossed 10 crore after 85 days, the ‘Tika Utsav’ or a special ‘vaccination festival’ was started till April 14.
“Anyone eligible for the vaccine should get the jab, and for this the society and administration have to make full efforts,” Prime Minister Modi said pitching for “zero vaccine waste” and urging the people to follow COVID-appropriate behaviour.
“This festival is, in a way, the beginning of another major war against corona. We have to lay special emphasis on personal hygiene as well as social hygiene,” he said.
Five states — Maharashtra, Chhattisgarh, Karnataka, Uttar Pradesh and Kerala — cumulatively account for 70.82 percent of India’s active COVID-19 cases, while Maharashtra alone accounts for 48.57 percent, the Union Health Ministry said.
Besides these states, Delhi, Tamil Nadu, Madhya Pradesh, Gujarat, Haryana, Rajasthan, Punjab, Telangana, Uttarakhand, Andhra Pradesh and West Bengal are displaying an upward graph in daily new cases.
Most of these states have reimposed restrictions, including the closure of schools, night curfew, weekend and local shutdowns, while ruling out a total lockdown, but as the latest wave of patients continues to flood hospitals, there are some signs of a rethink.
Maharashtra Chief Minister Uddhav Thackeray and his Delhi counterpart Arvind Kejriwal have said that a lockdown will be the only option if the infections don’t abate and the health system shows signs of collapsing.
Kejriwal on Sunday said the COVID-19 situation in the national capital is “very serious”.
The city recorded 10,774 fresh COVID-19 cases on Sunday, the highest single-day spike so far, with 48 more fatalities.
“The fourth wave is more dangerous than the previous wave, he told a press conference, and urged the people not to step out unless there is urgent work.
The chief minister said that his government does not want to impose lockdown in Delhi but such a situation may arise if there is a rush to the hospitals and beds are unavailable for serious patients.
“We need your cooperation. If your cooperation is received and the situation of hospitals is under control, there will be no need to impose lockdown in Delhi. But, if beds in the hospitals fell short and are unavailable, then lockdown may have to be imposed,” he said.
Speaking at an all-party meeting held virtually to discuss the COVID-19 situation in the state on Saturday, Maharashtra Chief Minister Uddhav Thackeray had indicated the imposition of a strict lockdown in the state given the alarming rise in COVID-19 cases.
“The number of patients is increasing so fast that if we do not decide on a lockdown today, a lockdown-like situation will automatically arise tomorrow, he said.
The state has already announced a slew of curbs, including night curfew.
As the number of active cases reaches a new high, states are grappling with the pressure on health facilities.
The Chhatttisgarh government has directed that 80 percent of the total oxygen produced will be supplied for medical purposes to hospitals.
The state health department on Sunday issued a notification in this regard under the Epidemic Diseases Act.
On Saturday, Chhattisgarh recorded 14,098 new cases of coronavirus, the highest single-day spike.
Several areas in Madhya Pradesh have been witnessing harried people queuing up outside medical stores for Remdesivir, a drug used in the treatment.
A senior Madhya Pradesh official on Sunday said a sizeable batch of the drug has arrived and will be distributed to medical facilities as per requirement.
Madhya Pradesh recorded 4,986 fresh coronavirus cases on Saturday, its biggest single-day spike.
In Maharashtra, Pune was also witnessing a huge demand for the drug.
Delhi government hospitals have been directed to engage fourth and fifth year MBBS students to meet the increased demand for manpower, while the tenure of senior and junior residents is being extended and vacant posts will be filled, officials said.
The Punjab Health Department has asked private hospitals to defer elective surgeries till April 30 to meet the increasing demand for beds and charge government-fixed rates for the treatment of coronavirus patients.
The Uttar Pradesh government announced imposing night curfew in districts reporting over 100 daily cases or 500 active cases and extended closure of all schools till April 30.
At the meeting chaired by Chief Minister Yogi Adityanath, it was decided to conduct at least one lakh RT-PCR tests daily.
Ahead of Navratri and Ramzan, the state government has said that not more than five persons should be allowed to enter religious places.
The state recorded highest-ever single-day spike of 15,353 cases, while 67 fresh deaths pushed the toll to 9,152.
The Gujarat government has already imposed restrictions on people’s movement during the night in 20 cities of the state, including Surat.
The latest surge of COVID-19 has also sparked concerns of a repeat of migrant workers’ exodus from the worst affected states.
Industry sources in Tamil Nadu said the sector was recovering from the jolt of the first wave of coronavirus but now some workers have again reportedly left for their natives early last week as they feared being stranded if a lockdown was imposed.
A severe spike in COVID-19 cases in Mumbai and talk of a “complete lockdown” like last year, has made the national highway number 3 skirting past Madhya Pradesh’s commercial hub Indore a prime route for wary migrants returning home to states like Uttar Pradesh and Bihar.
The number of motorcycles, black-and-yellow mini trucks and autorickshaws, teeming with migrants, have been on the rise over the past few days on a bypass road connected to this route, popularly known as Mumbai-Agra road.
“The virus outbreak has once again got very severe in Mumbai. There might be a lockdown and it may, like last year, render us jobless. So we have decided to return home,” said Ramsharan Singh (40), who was on his way back to Ballia in Uttar Pradesh in an autorickshaw.
Similar is the case with Mohammad Shadab, who is returning to his hometown in Bihar’s Bhojpur district.
“I work in a restaurant in Mumbai. I will think of returning there if the situation improves. Or else, I plan to stay back in Bihar and look for work,” he said.